A group of Nigerian scientists
have found what could be a
novel treatment for Human
Immune-deficiency Virus, HIV,
infection that may slash the
cost of treatment.
The team of scientists, including
graduate students and
researchers from the Michael
Okpara University of Agriculture,
Umudike, Abia state, University
of Nigeria, Nsukka, and the
Federal Medical Centre, Umuahia,
Nigeria have been able to show
that synthetic Aluminum-
magnesium silicate (AMS) has
antiretroviral effects that could
lay a perfect track for affordable
and effective therapy for HIV.
Results of their work titled
"Assessment of Antiretroviral
Effects of a Synthetic Aluminum-
magnesium Silicate" published in
the British Journal of Medicine &
Medical Research and featured
on nd featured on
SCIENCEDOMAIN international
shows a significant reduction in
the titres of the virus when HIV
positive plasma was incubated
with AMS.
Head, Department of Veterinary
Medicine at Michael Okpara
University of Agriculture, and the
lead scientist, Professor Maduike
Ezeibe, said the discovery could
provide an ultimate cure for the
virus that has defiled so many
scientific efforts to curtail it in
the past.
Ezeibe reacted aluminium silicate
with magnesium silicate to
obtain the synthetic aluminum-
magnesium silicate devoid of
impurities.
Giving further details Ezeibe
noted: "Molecules of aluminum-
magnesium silicate have
platelets that possess both
negative and positive electrical
charges on their surfaces and
their edges. HIV on the other
hand is negatively charged. So
the simple scientific
understanding that opposite
charges attracts ensures that the
HIV virus binds to the AMS and is
discharged from the body
alongside."
"AMS is normally used as a
stabilizing medicine that does
not really have toxic effect on
the patient, so it makes it a
suitable agent for mopping up
HIV virus from the body," he
said.
Ezeibe stated that "possession of
both negative and positive
electrical charges makes AMS a
broad spectrum antiviral
medicine."
"AMS, if used in combination of
selected antibiotics and immune
stimulant may achieve a 'cure'
for HIV," the lead researcher of
the work said.
"When a significant number of
particles of invading viruses
adsorb onto its (AMS) molecules
instead of onto their hosts cells,
viral infections are terminated,"
Ezeibe noted.
The author noted also that
"Adsorbing out HIV means that
millions of new virions usually
released from each infected cell
would be inhibited from
establishing new infections in
more cells," adding, "Thus, HIV
would be prevented from
overwhelming the body immune
systems and the Acquired
Immunodeficiency Syndrome
(AIDS) stage may be
prevented.which case Ezeibe
said a cure could be achieved.
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